This topic may be a US versus other countries thing in terms of on-line payment processing, so this comment is from a US perspective only.
Recently, I took a look at MoneyBookers for payment processing. In the US, people are accustomed to PayPal and confident in the system. PayPal fees are 2.9% +$.30/transaction, which is no bargain, unless you investigate the hassle of trying to process your own credit card payments.
As I was looking at MoneyBookers, I found that they are in the process of rebranding themselves as "Skrill". Skrill apparently is a slang term for money. Personally, Skrill sounds awful as a word, and it is not a widely used term in the US. Whether they will suceed with this rebranding is to be seen, but I would not have chosen that name for a payment processing system that needs to inspire confidence and needs to have appeal that cuts across demographic segments. Management's choice of Skrill for branding undermined my confidence in MoneyBookers, and I stopped looking at them as a payment processing alternative.